Synthesis and Antimicrobial Assay of Some Novel 4-Thiazolidinone Derivatives Possessing Benzofuran, Quinoline and Pyrazole Moieties
نویسندگان
چکیده
منابع مشابه
Design, Synthesis and Antimicrobial Evaluation of Some Novel Quinoline Derivatives
The Global Burden of Disease Study(GBDS) estimates that infectious diseases were responsible for 22% of all deaths and 27% of disability-adjusted life years (DALYS ) worldwide according to WHO [1]. Antimicrobial resistance among clinically important bacteria is widely acknowledged as a major global public health threat [2]. Most of the currently used antimicrobial drugs are associated with adve...
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Benzofurans are very interesting heterocycles, which are available in nature and show a wide range of pharmacological activities. Hence, different benzofurans having 4-thiazolidinones have been synthesized for the purpose of pharmacological evaluation. The desired compounds were prepared using simple starting materials like salicylaldehyde and ethyl bromoacetate. The reaction between these comp...
متن کاملSynthesis of Some 4-Thiazolidinone Derivatives as Antitubercular Agents
Substituted Schiff's bases 2a-o prepared by the treatment of 2-amino-4-(?-methoxyiminocarbomethoxymethyl)-thiazole 1 with different aromatic aldehydes, on cyclocondensation with mercaptoaceticacid and mercaptopropionicacid in dry benzene furnished desired thiazolidinones of type 3a-o and 4a-j, respectively. The structure of the compounds have been assigned on the basis of elemental analyses and...
متن کاملSynthesis and Biological Investigation of some Novel Sulfonamide and Amide Derivatives Containing Coumarin Moieties
New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamide derivatives and a wide range of coumarins. The structures of the obtained compounds were elucidated by IR and NMR spectra and also analytical elemental analysis. In the next step, the above mention...
متن کاملSynthesis and Biological Investigation of some Novel Sulfonamide and Amide Derivatives Containing Coumarin Moieties
New sulfonamide and amide derivatives containing coumarin moieties; oxo-2H-chromen-sulfamoylphenylacetamides and oxo-2H-chromen-arylacetamides were synthesized starting from diverse 2-chloroacetamide derivatives and a wide range of coumarins. The structures of the obtained compounds were elucidated by IR and NMR spectra and also analytical elemental analysis. In the next step, the above mention...
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ژورنال
عنوان ژورنال: Asian Journal of Chemistry
سال: 2018
ISSN: 0970-7077,0975-427X
DOI: 10.14233/ajchem.2018.21522